STATE-SPECIFIC MORPHOLOGICAL DEFORMATIONS OF THE LIPID BILAYER EXPLAIN MECHANOSENSITIVE GATING OF MSCS ION CHANNELS

State-specific morphological deformations of the lipid bilayer explain mechanosensitive gating of MscS ion channels

The force-from-lipids hypothesis of cellular mechanosensation posits that membrane channels open and close in response to changes in the physical state of the lipid bilayer, induced for example by lateral tension.Here, we investigate the molecular basis for this transduction mechanism by studying the mechanosensitive ion channel MscS from Escherich

read more

Flow Unit Model of Channel Sand Body and Its Effect on Remnant Oil Distribution: A Case Study of PI Formation in the Eastern Transition Zone of Daqing Oilfield

To analyze the effect of various flow units in a channel sand body on remnant oil, we established a connection between various flow unit types and the remnant oil distribution.Using stratigraphic correlation and the characterization of sedimentary microfacies, we describe a single sand body, point bar, and narrow channel located at the injection-pr

read more

Acupuncture for acute musculoskeletal pain management in the emergency department and continuity clinic: a protocol for an adaptive pragmatic randomised controlled trial

Introduction Chronic musculoskeletal pain causes a significant burden on health and iphone 14 price miami quality of life and may result from inadequate treatment of acute musculoskeletal pain.The emergency department (ED) represents a novel setting in which to test non-pharmacological interventions early in the pain trajectory to prevent the trans

read more

Fear and loathing in Lithuania

As an EU-member, Lithuania has to a large extent set up institutional mechanisms to combat homophobia.It has implemented anti-discrimination laws that are roughly in line with EU norms.At the same time, the country sten jacket m does not allow same-sex marriage, fails to recognize same-sex partnership (or indeed any form of civil partnership), and

read more